PostDoc (gn*) Physiology and Biophysics of Ion Channels in Human Sperm

Job ID: 11720

Fixed term of 3 years | Full-time with 100 % | Salary according to TV-L E13 | Centre of Reproductive Medicine and Andrology

We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility – ideally with you on board!

The position is located in the research group of Timo Strünker (Molecular Reproductive Physiology) and embedded in the DGF-funded Collaborative Research Centre 1748 ‘Principles of Reproduction’. The CRC 1748 involves scientists of the University, University Hospital, and Max Planck Institute Münster as well as of the RWTH Aachen. Our central objective is to elucidate the genetic, molecular, and cellular mechanisms governing the formation and function of the testis, production and function of sperm, fertilisation, as well as early embryonic development – in both health and disease. To this end, we combine interdisciplinary research in molecular, structural, and cell biology as well as in physiology, biophysics, epi /genetics, (bio)informatics, and multimodal data analysis.

In this project, we will elucidate the molecular mechanisms that enable sperm to sense their chemical and physical environment, with a particular focus on ion channels and signalling molecules, proteins, and pathways.

RESPONSIBILITIES:

• Analysing the biophysical properties of sperm-specific ion channels
• Dissecting the interplay of ion channels in human sperm
• Performing patch-clamp recordings from somatic cells and human sperm cells in combination with the use of caged compounds

REQUIREMENTS:

• PhD in biology, biochemistry, pharmacy, physics, biomedicine or other life sciences
• Strong interest in physiology and biophysics of ion channels
• Experience in studying ion channels using patch-clamp recordings
• High motivation for scientific work and willingness to contribute to an interdisciplinary team
• Commitment to research in a translational setting
• Excellent English communication skills (spoken and written); German skills are advantageous
• Knowledge of the use of photochemical tools, e.g., caged compounds (desired)

WE OFFER:

• Salary according to tariff agreement, extra annual payment, and company pension plan (VBL)
• 30 days of vacation per year, plus two additional days off on Christmas Eve and New Year's Eve
• State-of-the-art techniques, tools, and experimental models for research
• Competitive, interdisciplinary, creative, and international research environment with a track record of intense mutual collaboration
• A respectful and appreciative work environment within a diverse team
• Support and advisory services for health and work-life balance
• Additional benefits such as sports programs, job ticket, company events, cafeteria, and emergency childcare

For inquiries, please contact: Christoph Brenker, [email protected] , T 0251-8358240

Apply now via our career portal by February 18, 2026 including:

• Letter of motivation (max 2 pages) Summary of your doctoral thesis (max 1 page) Transcript and scanned copies of your degree certificates Names and contact details of two references

Applications of women are specifically invited. In the case of similar qualifications, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference. Due to legal requirements working with us is only permitted with complete vaccination against measles.

(*gn=gender neutral)